Atarax 0 25mg

Following administration of hydroxyzine to animals, the drug is widely distributed into most body tissues and fluids with highest concentrations in the liver, lungs, spleen, atarax 0 25mg, kidneys, and adipose tissue.

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The drug is also distributed into bile in animals. Hydroxyzine crosses the placental barrier which may lead to higher foetal than maternal concentrations, atarax 0 25mg.

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Serum hydroxyzine concentrations atarax not necessarily reflect hydroxyzine tissue binding or distribution to skin receptor sites. Suppression of wheals, 25mg, and associated 25mg has been shown to persist even when serum atarax concentrations are low. First-generation H1 antagonists easily cross the blood-brain barrier. In a study group of healthy adults, the mean apparent volume of distribution has been found to be Biotransformation Hydroxyzine is metabolised in the liver.

Metabolites include cetirizine, which has antihistaminic activity, atarax 0 25mg.

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Cetirizine is formed from hydroxyzine via an 25mg biotransformation step. Elimination An elimination half life of Hydroxyzine is eliminated by hepatic atarax in humans, atarax 0 25mg.

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Cetirizine is mainly renally excreted, atarax 0 25mg. Special populations Elderly patients The pharmacokinetics of hydroxyzine were studied in nine healthy elderly mean age The mean serum elimination half life value of hydroxyzine in this elderly group was The mean apparent volume of distribution of hydroxyzine in this elderly group was Hydroxyzine has a long mean serum elimination half life value, a large volume atarax distribution and a prolonged pharmacodynamics effect suppressive effect on wheal and flare response to histamine in the elderly.

In the elderly a number of age-related biological and physiological changes may have an effect on the 25mg of hydroxyzine and its metabolite, atarax 0 25mg, cetirizine.

atarax 0 25mg

These changes may impact upon the pharmacologic functions of absorption, distribution, metabolism, excretion, atarax 0 25mg, and 25mg sensitivity. Dosage reduction may be appropriate in elderly patients see section 4. The children were given a single orally atarax dose of 0. The mean peak serum concentration atarax Terminal elimination half life was 25mg in children than in adults, at a mean of 7. This resulted from a larger clearance rate in children of The elimination half-life values increased with increasing age.

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Half life atarax were atarax 4 hours in the 1 year old patients and 11 hours in the 14 year old patient, atarax 0 25mg. Dosage should be adjusted in the 25mg population see section 4. All patients had abnormal liver biochemistry tests, all had biopsies compatible with primary biliary cirrhosis, and seven of eight had positive tests for antimitochondrial antibodies.

Before you take Atarax, tell your doctor if you have a seizure disorder, liver disease, or kidney disease. This medication may impair your thinking or reactions, atarax 0 25mg.

Be careful if you drive 25mg do anything that requires you to be alert. Stop using Atarax and call your doctor at once if you have a serious side effect such as tremors, confusion, seizures, atarax 0 25mg, or restless muscle movements in your eyes, tongue, jaw, or neck.

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Drinking alcohol can increase certain side effects of hydroxyzine. Before taking this medicine You should not use Atarax if you are allergic to hydroxyzine, or if you are pregnant. To make sure you can safely take Atarax, atarax 0 25mg, tell your doctor if you have any of these other conditions: Do not use Atarax without telling your doctor if you are pregnant.

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It could harm 25mg unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment. It is not known whether hydroxyzine passes into breast milk or if it could harm a nursing baby, atarax 0 25mg. Do not use this medication without telling your doctor atarax you are breast-feeding a baby.

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Older adults may be more likely to have side effects from this medication. How should I take Atarax?

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Take Atarax exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

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Take this medicine with a full glass of water. Measure Atarax syrup with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Store at room temperature away from moisture and heat.

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